Constitutive and Ghrelin-Dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons
The growth hormone secretagogue receptor type 1a (GHSR1a) has the highest known constitutive activity of any G Protein-Coupled receptor (GPCR). GHSR1a mediates the action of the hormone ghrelin, and its activation increases transcriptional and electrical activity in hypothalamic neurons. Although GH...
Guardado en:
| Autores principales: | López Soto, Eduardo Javier, Agosti, Francina, Cabral, Agustina Soledad, Mustafá, Emilio Román, Martínez Damonte, Valentina, Gandini, M. A., Rodríguez, Silvia Susana, Castrogiovanni, Daniel, Felix, R., Perelló, Mario, Raingo, Jesica |
|---|---|
| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2015
|
| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/87274 |
| Aporte de: |
Ejemplares similares
-
Ghrelin Selectively Inhibits CaV3.3 Subtype of Low-Voltage-Gated Calcium Channels
por: Mustafá, Emilio Román, et al.
Publicado: (2020) -
Constitutive activity of the Ghrelin receptor reduces surface expression of voltage-gated Ca2+ channels in a CaVβ-dependent manner
por: Mustafá, Emilio Román, et al.
Publicado: (2017) -
La actividad constitutiva del receptor de ghrelina reduce la expresión en superficie de
los canales de Ca2+ (CaV) dependientes de voltaje de manera dependiente de CaVβ
por: Mustafá, Emilio Román, et al.
Publicado: (2019) -
CaV2.1 (P/Q) voltage activated Ca2+ channels and synaptic transmission in genetic and autoimmune diseases
por: Uchitel, O.D. -
CaV2.1 (P/Q) voltage activated Ca2+ channels and synaptic transmission in genetic and autoimmune diseases
por: Uchitel, Osvaldo Daniel
Publicado: (2013)