Characterization of a P-Rex1 gene signature in breast cancer cells

The Rac nucleotide Exchange Factor (Rac-GEF) P-Rex1 is highly expressed in breast cancer, specifically in the luminal subtype, and is an essential mediator of actin cytoskeleton reorganization and cell migratory responses induced by stimulation of ErbB and other tyrosine-kinase receptors. Heregulin...

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Detalles Bibliográficos
Autores principales: Barrio Real, Laura, Wertheimer, Eva, Garg, Rachana, Abba, Martín Carlos, Kazanietz, Marcelo G.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2016
Materias:
Ciencias Médicas
Breast cancer
Heregulin
MMP10
P-Rex1
Rac1
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/86669
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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