Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice
Loss of strength in human and animal models of aging can be partially attributed to a well-recognized decrease in muscle mass; however, starting at middle-age, the normalized force (force/muscle cross-sectional area) in the knee extensors and single muscle fibers declines in a curvilinear manner. St...
Guardado en:
| Autores principales: | Zhang, Tan, Pereyra, Andrea Soledad, Wang, Zhong-Min, Birbrair, Alexander, Reisz, † Julie A., Files, Daniel Clark, Purcell, Lina, Feng, Xin, Messi, Lina, Feng, Hanzhong, Chalovich, Joseph, Jin, Jian-Ping, Furdui, Cristina, Delbono, Osvaldo |
|---|---|
| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/85773 |
| Aporte de: |
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