Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na+‒HCO¯3 cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: Role of the renin-angiotensin system

Aims. Electroneutral (NBCn1) and electrogenic (NBCe1) isoforms of the Na<SUP>+</SUP>‒HCO¯<SUB>3</SUB> cotransporter (NBC) coexist in the heart. We studied the expression and function of these isoforms in hearts of Wistar and spontaneously hypertensive rats (SHR), elucidating...

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Detalles Bibliográficos
Autores principales:	Orlowski, Alejandro, Ciancio, María Carolina, Caldiz, Claudia Irma, De Giusti, Verónica Celeste, Aiello, Ernesto Alejandro
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2014
Materias:	Ciencias Médicas Cardiac hypertrophy Cardiac myocytes Na+‒HCO¯3 cotransporter
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/85081
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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