Identification of levothyroxine antichagasic activity through computer-aided drug repurposing
Cruzipain (Cz) is the major cysteine protease of the protozoan <i>Trypanosoma cruzi</i>, etiological agent of Chagas disease. A conformation-independent classifier capable of identifying Cz inhibitors was derived from a 163-compound dataset and later applied in a virtual screening campai...
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| Autores principales: | Bellera, Carolina Leticia, Balcazar, Darío E., Alberca, Lucas Nicolás, Labriola, Carlos A., Talevi, Alan, Carrillo, Carolina |
|---|---|
| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/85048 |
| Aporte de: |
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