The role of hydration on the mechanism of allosteric regulation: In situ measurements of the oxygen-linked kinetics of water binding to hemoglobin

We report here the first direct measurements of changes in protein hydration triggered by a functional binding. This task is achieved by weighing hemoglobin (Hb) and myoglobin films exposed to an atmosphere of 98% relative humidity during oxygenation. The binding of the first oxygen molecules to Hb...

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Autores principales: Salvay, Andrés Gerardo, Grigera, José Raúl, Colombo, Marcio F.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2003
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/84881
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