Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline

As-p18 is a fatty-acid-binding protein from the parasitic nematode Ascaris suum. Although it exhibits sequence similarity to mammalian intracellular fatty-acid-binding proteins, it contains features that are unique to nematodes. Crystals were obtained, but initial diffraction data analysis revealed...

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Detalles Bibliográficos
Autores principales: Gabrielsen, Mads, Riboldi-Tunnicliffe, Alan, Ibáñez Shimabukuro, Marina, Griffiths, Kate, Roe, Andrew J., Cooper, Alan, Smith, Brian O., Córsico, Betina, Kennedy, Malcolm W.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Bioquímica
Ascaris suum
fatty-acid-binding proteins
microfocus beamlines
parasitic nematodes
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/84572
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
Descripción
Sumario:As-p18 is a fatty-acid-binding protein from the parasitic nematode Ascaris suum. Although it exhibits sequence similarity to mammalian intracellular fatty-acid-binding proteins, it contains features that are unique to nematodes. Crystals were obtained, but initial diffraction data analysis revealed that they were composed of a number of microdomains. Interpretable data could only be collected using a microfocus beamline with a beam size of 12 8 m.

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