Determination of esomeprazole in rabbit plasma by liquid chromatography-mass spectrometry and its application to a pharmacokinetic study
A sensitive and selective liquid chromatography-mass spectrometry (LC–MS) method for determination of esomeprazole in rabbit plasma was developed and validated. After addition of midazolam as internal standard (IS), protein precipitation by acetonitrile was used as sample preparation, and chromatogr...
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| Autores principales: | Zhang, Meiling, Wang, Xuebao, Wang, Zhiyi, Deng, Mingjie, Xu, Zhisheng, Zheng, Yuancai, Zhang, Yuan, Huang, Xueli |
|---|---|
| Formato: | Articulo Comunicacion |
| Lenguaje: | Inglés |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8447 http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_2_6.pdf |
| Aporte de: |
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