Role of phosphorylation of Thr17 residue of phospholamban in mechanical recovery during hypercapnic acidosis

Objectives: To assess the time course of phosphorylation of phospholamban residues, the underlying mechanisms determining these phosphorylations, and their functional impact on the mechanical recovery during acidosis. Methods: Langendorff perfused rat hearts were submitted to 30 min of hypercapnic...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mundiña-Weilenmann, Cecilia, Ferrero, Paola Viviana, Said, María Matilde, Vittone, Leticia, Kranias, Evangelia G., Mattiazzi, Alicia Ramona
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2005
Materias:	Ciencias Médicas CaMKII Contractile function Myocardial acidosis Na+/Ca2+ exchanger Phospholamban phosphorylation
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/84354
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

Ejemplares similares

Ca2+/calmodulin-dependent protein kinase: A key component in the contractile recovery from acidosis
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2007)

Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors
por: Valverde, Carlos Alfredo, et al.
Publicado: (2018)

The role of CaMKII regulation of phospholamban activity in heart disease
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2014)

Mechanisms involved in the acidosis enhancement of the isoproterenol-induced phosphorylation of phospholamban in the intact heart
por: Vittone, Leticia Beatriz, et al.
Publicado: (1998)

Role of phospholamban phosphorylation on Thr17 in cardiac physiological and pathological conditions
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2005)

CaMKII regulation of phospholamban and SR Ca<SUP>2+</SUP> load
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2011)

Role of Ca2+-calmodulin dependent phospholamban phosphorylation on the relaxant effect of β-adrenergic agonists
por: Vittone, Leticia Beatriz, et al.
Publicado: (1993)

La vía de señalización de la quinasa dependiente de Ca+2 y calmodulina sostiene el efecto inotrópico positivo de la estimulación b-adrenérgica prolongada
por: Quiroga, Diego, et al.
Publicado: (2015)

CaMKII-dependent responses to ischemia and reperfusion challenges in the heart
por: Bell, James R., et al.
Publicado: (2014)

Phospholamban: a tiny protein with a prominent role in the regulation of cardiac relaxation and contractility
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2010)

The importance of the Thr<SUP>17</SUP> residue of phospholamban as a phosphorylation site under physiological and pathological conditions
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2006)

CaMKII-dependent ryanodine receptor phosphorylation mediates sepsis-induced cardiomyocyte apoptosis
por: Sepúlveda, Marisa Noemí, et al.
Publicado: (2020)

The multifunctional Ca²⁺/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin’s spring elements
por: Hidalgo, Carlos, et al.
Publicado: (2012)

CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury
por: Vila Petroff, Martín Gerardo, et al.
Publicado: (2007)

Chasing cardiac physiology and pathology down the CaMKII cascade
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2015)

Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias
por: Gonano, Luis Alberto, et al.
Publicado: (2011)

Frequency-dependent acceleration of relaxation in mammalian heart: a property not relying on phospholamban and SERCA2a phosphorylation
por: Valverde, Carlos Alfredo, et al.
Publicado: (2005)

Ca<SUP>2+</SUP>/calmodulin kinase II increases ryanodine binding and Ca<SUP>2+</SUP>-induced sarcoplasmic reticulum Ca<SUP>2+</SUP> release kinetics during beta-adrenergic stimulation
por: Ferrero, Paola Viviana, et al.
Publicado: (2007)

Angiotensin II-induced oxidative stress resets the Ca2+ dependence of Ca2+-calmodulin protein kinase II and promotes a death pathway conserved across different species
por: Palomeque, Julieta, et al.
Publicado: (2009)

El estrés del retículo endoplasmático inducido por isquemia y reperfusión (I/R) del miocardio : Su relación con la activación de la quinasa dependiente de calcio y calmodulina (CAMKII)
por: Di Carlo, Mariano Nahuel, et al.
Publicado: (2016)

Sustained CaMKII Delta Gene Expression Is Specifically Required for Long-Lasting Memories in Mice
por: Zalcman, G., et al.

Sustained CaMKII Delta Gene Expression Is Specifically Required for Long-Lasting Memories in Mice
Publicado: (2019)

Nitric oxide and CaMKII: Critical steps in the cardiac contractile response To IGF-1 and swim training
por: Burgos, Juan Ignacio, et al.
Publicado: (2017)

Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes
por: Lezcano, Noelia, et al.
Publicado: (2018)

Phospholamban phosphorylation sites enhance the recovery of intracellular Ca2+ after perfusion arrest in isolated, perfused mouse heart
por: Valverde, Carlos Alfredo, et al.
Publicado: (2006)

Immunodetection of phosphorylation sites gives new insights into the mechanisms underlying phospholamban phosphorylation in the intact heart
por: Mundiña-Weilenmann, Cecilia, et al.
Publicado: (1996)

The oxidative activation of Ca²⁺/calmodulin-dependent protein kinase II: a double-edged sword for health and disease
por: Wang, Qinchuan
Publicado: (2022)

A putative mechanism of age-related synaptic dysfunction based on the impact of IGF-1 receptor signaling on synaptic CaMKIIα phosphorylation
por: Ogundele, Olalekan Michael, et al.
Publicado: (2018)

Cardiotoxicidad del estado de tolerancia a la glucosa alterada : Mecanismos intracelulares y rol de la Ca2+-Calmodulina Kinasa II
por: Sommese, Leandro Matías
Publicado: (2018)

CaMKII isoforms in learning and memory: Localization and function
por: Zalcman, G., et al.

CaMKII isoforms in learning and memory: Localization and function
Publicado: (2018)

El óxido nítrico como modulador de la proteína quinasa II dependiente de Ca<SUP>2+</SUP> y calmodulina cardíaca
por: Burgos, Juan Ignacio
Publicado: (2018)

Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814
por: Mazzocchi, Gabriela, et al.
Publicado: (2016)

Unbalance Between Sarcoplasmic Reticulum Ca<sup>2+</sup> Uptake and Release: A First Step Toward Ca<sup>2+</sup> Triggered Arrhythmias and Cardiac Damage
por: Federico, Marilén, et al.
Publicado: (2020)

Proteínas asociadas al manejo del calcio intracelular en el miocardio como blancos potenciales de modificaciones redox
por: Román, Bárbara Soledad
Publicado: (2018)

Pautas para prevenir la acidosis.
por: Gorosito, Ramón

Lusitropic effects of α- and β-adrenergic stimulation in amphibian heart
por: Vila Petroff, Martín Gerardo, et al.
Publicado: (1994)

Mechanisms Underlying the Increase in Force and Ca<sup>2+</sup> Transient That Follow Stretch of Cardiac Muscle : A Possible Explanation of the Anrep Effect
por: Álvarez, Bernardo Víctor, et al.
Publicado: (1999)

Frequency-dependent changes in calcium cycling and contractile activation in SERCA2a transgenic mice
por: Hashimoto, Katsuji, et al.
Publicado: (2000)

Contractile recovery from acidosis in toad ventricle is independent of intracellular pH and relies upon Ca2+ influx
por: Salas, Margarita Ana, et al.
Publicado: (2006)