Increased brain radioactivity by intranasal 32P-labeled siRNA dendriplexes within in situ-forming mucoadhesive gels

Background: Molecules taken up by olfactory and trigeminal nerve neurons directly access the brain by the nose-to-brain pathway. In situ-forming mucoadhesive gels would increase the residence time of intranasal material, favoring the nose-to-brain delivery. In this first approach, brain radioactivit...

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Detalles Bibliográficos
Autores principales: Pérez, Ana Paula, Mundiña-Weilenmann, Cecilia, Romero, Eder Lilia, Morilla, María José
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Ciencias Médicas
Dendrimers
Gel
Mucosa
Nucleic acids
Olfactory bulb
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/84345
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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