Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias

Background-Digitalis-induced Na + accumulation results in an increase in Ca 2+ i via the Na +/Ca 2+ exchanger, leading to enhanced sarcoplasmic reticulum (SR) CaCa 2+ load, responsible for the positive inotropic and toxic arrhythmogenic effects of glycosides. A digitalis-induced increase in Ca 2+ i...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gonano, Luis Alberto, Sepúlveda, Marisa Noemí, Rico, Yanina, Kaetzel, Marcia, Valverde, Carlos Alfredo, Dedman, John, Mattiazzi, Alicia Ramona, Vila Petroff, Martín Gerardo
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2011
Materias:	Ciencias Médicas Arrhythmias CaMKII Cardiotonic steroids Heart failure
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/84091
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

Ejemplares similares

Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors
por: Valverde, Carlos Alfredo, et al.
Publicado: (2018)

The role of CaMKII regulation of phospholamban activity in heart disease
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2014)

Ca2+/calmodulin-dependent protein kinase: A key component in the contractile recovery from acidosis
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2007)

Chasing cardiac physiology and pathology down the CaMKII cascade
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2015)

Calcium triggered arrhythmias and the goldilocks’ principle
por: Valverde, Carlos Alfredo, et al.
Publicado: (2022)

Angiotensin II-induced oxidative stress resets the Ca2+ dependence of Ca2+-calmodulin protein kinase II and promotes a death pathway conserved across different species
por: Palomeque, Julieta, et al.
Publicado: (2009)

The multifunctional Ca²⁺/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin’s spring elements
por: Hidalgo, Carlos, et al.
Publicado: (2012)

The oxidative activation of Ca²⁺/calmodulin-dependent protein kinase II: a double-edged sword for health and disease
por: Wang, Qinchuan
Publicado: (2022)

La vía de señalización de la quinasa dependiente de Ca+2 y calmodulina sostiene el efecto inotrópico positivo de la estimulación b-adrenérgica prolongada
por: Quiroga, Diego, et al.
Publicado: (2015)

Thoracic vein arrhythmias mechanisms and treatment /
Publicado: (2004)

Ca<SUP>2+</SUP>/calmodulin kinase II increases ryanodine binding and Ca<SUP>2+</SUP>-induced sarcoplasmic reticulum Ca<SUP>2+</SUP> release kinetics during beta-adrenergic stimulation
por: Ferrero, Paola Viviana, et al.
Publicado: (2007)

Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca2+ release events in a rodent model of early stage diabetes: The arrhythmogenic substrate
por: Sommese, Leandro Matías, et al.
Publicado: (2016)

CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury
por: Vila Petroff, Martín Gerardo, et al.
Publicado: (2007)

CaMKII-dependent ryanodine receptor phosphorylation mediates sepsis-induced cardiomyocyte apoptosis
por: Sepúlveda, Marisa Noemí, et al.
Publicado: (2020)

CaMKII-dependent responses to ischemia and reperfusion challenges in the heart
por: Bell, James R., et al.
Publicado: (2014)

El estrés del retículo endoplasmático inducido por isquemia y reperfusión (I/R) del miocardio : Su relación con la activación de la quinasa dependiente de calcio y calmodulina (CAMKII)
por: Di Carlo, Mariano Nahuel, et al.
Publicado: (2016)

Sustained CaMKII Delta Gene Expression Is Specifically Required for Long-Lasting Memories in Mice
por: Zalcman, G., et al.

Sustained CaMKII Delta Gene Expression Is Specifically Required for Long-Lasting Memories in Mice
Publicado: (2019)

New arrhythmia technologies
Publicado: (2005)

Role of phosphorylation of Thr17 residue of phospholamban in mechanical recovery during hypercapnic acidosis
por: Mundiña-Weilenmann, Cecilia, et al.
Publicado: (2005)

Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes
por: Lezcano, Noelia, et al.
Publicado: (2018)

Serial determination of systolic time intervals in myocardial infarction: correlation with the clinical picture and the systolic volume
por: Caiafa, P.M., et al.

Serial determination of systolic time intervals in myocardial infarction: correlation with the clinical picture and the systolic volume
Publicado: (1974)

Cardiotoxicidad del estado de tolerancia a la glucosa alterada : Mecanismos intracelulares y rol de la Ca2+-Calmodulina Kinasa II
por: Sommese, Leandro Matías
Publicado: (2018)

Catheter ablation of cardiac arrhythmias basic concepts and clinical applications /
Publicado: (2008)

Electrophysiology : the basics : a companion guide for the cardiology fellow during the EP rotation /
Publicado: (2010)

Nitric oxide and CaMKII: Critical steps in the cardiac contractile response To IGF-1 and swim training
por: Burgos, Juan Ignacio, et al.
Publicado: (2017)

Clinical cardiac electrophysiology : techniques and interpretations /
por: Josephson, Mark E.
Publicado: (2008)

Tracking nitroxyl-derived posttranslational modifications of phospholamban in cardiac myocytes
por: Mundiña-Weilenmann, Cecilia, et al.
Publicado: (2019)

Heart failure : a practical guide for diagnosis and management /
por: Katz, Stuart D.
Publicado: (2013)

CaMKII isoforms in learning and memory: Localization and function
por: Zalcman, G., et al.

CaMKII isoforms in learning and memory: Localization and function
Publicado: (2018)

A putative mechanism of age-related synaptic dysfunction based on the impact of IGF-1 receptor signaling on synaptic CaMKIIα phosphorylation
por: Ogundele, Olalekan Michael, et al.
Publicado: (2018)

El óxido nítrico como modulador de la proteína quinasa II dependiente de Ca<SUP>2+</SUP> y calmodulina cardíaca
por: Burgos, Juan Ignacio
Publicado: (2018)

Digitalis poisoning
por: Masanti, J.G.

Digitalis poisoning
Publicado: (1977)

Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814
por: Mazzocchi, Gabriela, et al.
Publicado: (2016)

Cardenolide glycosides from the roots of mandevilla pentlandiana
por: Cabrera, G.M., et al.

Cardenolide glycosides from the roots of mandevilla pentlandiana
por: Cabrera, Gabriela Myriam, et al.
Publicado: (1993)

A Practical Approach to Clinical Arrhythmology /
Publicado: (2010)