Synthesis and preliminary pharmacological evaluation of methoxilated indoles with possible dopaminergic central action

Compounds 5-7 were synthesized from 4-tetralones with o-iodoanilines by a radical nucleophilic substitution or SRN1 reaction, and were pharmacologically evaluated in order to establish their possible antagonistic action on the central dopaminergic receptors. Behavioural parameters, such as stereotyp...

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Detalles Bibliográficos
Autores principales: Enriz, Ricardo Daniel, Herrera Cano, Natividad, Ortega, José, Ramírez, María M., Israel, Anita, Suárez Roca, Heberto, Charris, Jaime E., Rosales, Cecire, Hernández, Verónica, Andujar, Sebastian, Barolo, Silvia, De Ángel, Biagina Migliore, Rossi, Roberto, Santiago, Ana, Angel Guío, Jorge E.
Formato: Articulo
Lenguaje:Español
Publicado: 2011
Materias:
Farmacia
Agentes Neurotransmisores
Antagonistas de Dopamina
Receptores Dopaminérgicos
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8398
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_10.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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