QSAR studies on aminopyrazoles for the prediction of inhibition of CDK2/Cyclin A as antitumor agents

Cylin dependent kinases (CDKs) have emerged as novel mechanistic target due to their direct involvement in underlying genetic changes during the cancerous state. In order to identify the essential physiochemical parameters for CDK2 inhibitory activity in some 3-aminopyrazole derivatives, Quantitativ...

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Autores principales: Jain, Sonika, Kishore, Dharma, Dwivedi, Jaya
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8389
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_1.pdf
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