Reversible and time-dependent inhibition of CYP3A4-mediated nifedipine oxidation by noscapine

Substrate-dependent inhibition of CYP3A4 might influence the extrapolation of drug interactions from the in vitro to in vivo situation. The aim of the present study is to investigate reversible and time-dependent inhibition of CYP3A4-mediated nifedipine oxidation by noscapine. Furthermore, in vitroi...

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Detalles Bibliográficos
Autores principales: Wang, Li-Ming, Yang, Ling, Li, Ming, Sun, De-Guang, Tang, Bo, Gao, Zhen-Ming, Liang, Rui, Qu, Yan-Qing, Fang, Zhong-Ze, Tang, Shu-Hong, Jin, Xue Li
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
Warfarina
Sustratos
Noscapina
Nifedipino
Interacciones de Drogas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8385
http://www.latamjpharm.org/resumenes/30/9/LAJOP_30_9_2_2.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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