Potential use of cellulose acetate butyrate and pluronic F68® blends in the modulation of the diclofenac sodium release from microspheres

Microspheres were prepared using the emulsion/solvent evaporation method with the aim of obtaining diclofenac sodium (DFS) prolonged release dosage forms. The effects of the drug:polymer ratio and addition of Pluronic F68® to the formulations on drug content, particle size and DFS release rate were...

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Autores principales: Medeiros, Daniela C. de, Soldi, Valdir, Poli, Anicleto, Lemos Senna, Elenara
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8376
http://www.latamjpharm.org/resumenes/30/9/LAJOP_30_9_1_20.pdf
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