Improvement of anti inflammatory activity of quercetin with cyclodextrin complexes
The objective of this study was to enhance the anti-inflammatory activity of quercetin through complexation, by kneading method, with β cyclodextrin (βCD), hydroxy propyl β cyclodextrin (HP-βCD), and sulpha butyl ether β cyclodextrin (SBE-βCD). The anti inflammatory activity was determined by rat pa...
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| Autores principales: | , , |
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| Formato: | Articulo Comunicacion |
| Lenguaje: | Inglés |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8353 http://www.latamjpharm.org/resumenes/30/8/LAJOP_30_8_2_5.pdf |
| Aporte de: |
| Sumario: | The objective of this study was to enhance the anti-inflammatory activity of quercetin through complexation, by kneading method, with β cyclodextrin (βCD), hydroxy propyl β cyclodextrin (HP-βCD), and sulpha butyl ether β cyclodextrin (SBE-βCD). The anti inflammatory activity was determined by rat paw edema method. The anti-inflammatory activity of the kneaded complexes of quercetin- βCD/ HP-βCD/ SBE-βCD inclusion complexes demonstrated enhanced of anti-inflammatory activity in the order SBE-βCD> HP-βCD> βCD > pure quercetin. |
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