Role of phospholamban phosphorylation on Thr17 in cardiac physiological and pathological conditions

The sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA2a) is under the control of a closely associated SR protein named phospholamban (PLN). Dephosphorylated PLN inhibits the SR Ca2+ pump, whereas phosphorylation of PLN, at either Ser16 by PKA or Thr17 by calmodulin-dependent protein kinase II (CaMKII),...

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Autores principales: Mattiazzi, Alicia Ramona, Mundiña-Weilenmann, Cecilia, Guoxiang, Chu, Vittone, Leticia, Kranias, Evangelia
Formato: Articulo
Lenguaje:Inglés
Publicado: 2005
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/83507
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