Phospholamban phosphorylation sites enhance the recovery of intracellular Ca2+ after perfusion arrest in isolated, perfused mouse heart

Objective: To investigate the importance of the phosphorylation of Ser16 and Thr17 sites of phospholamban (PLN) on intracellular Ca2+ (Cai2+) handling and contractile recovery of the stunned myocardium. Methods: Cai2+ (Rhod-2, pulsed local-field fluorescence microscopy) and contractility (isovolumic...

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Detalles Bibliográficos
Autores principales:	Valverde, Carlos Alfredo, Mundiña-Weilenmann, Cecilia, Reyes, Mariano, Kranias, Evangelia G., Escobar, Ariel L., Mattiazzi, Alicia Ramona
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2006
Materias:	Ciencias Médicas Intracellular calcium Ischemia-reperfusion Myofibrillar proteins Phospholamban mutants Phospholamban phosphorylation residues
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/83099
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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