CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury

Objectives: Ca2+/calmodulin-dependent protein kinase II (CaMKII) has been implicated in the regulation of cardiac excitation-contraction coupling (ECC) as well as in apoptotic signaling and adverse remodeling. The goal of the present study is to investigate the role of CaMKII in irreversible ischemi...

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Detalles Bibliográficos
Autores principales: Vila Petroff, Martín Gerardo, Salas, Margarita Ana, Said, María Matilde, Valverde, Carlos Alfredo, Sapia, Luciana, Portiansky, Enrique Leo, Hajjar, Roger J., Kranias, E. G., Mundiña-Weilenmann, Cecilia, Mattiazzi, Alicia Ramona
Formato: Articulo
Lenguaje:Inglés
Publicado: 2007
Materias:
Ciencias Médicas
Apoptosis
CaMKII
Ischemia/reperfusion injury
Myocardium
Necrosis
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/82965
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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