Anticataleptic activity of various extracts of the aerial parts of Achyranthes aspera
Achyranthes aspera is traditionally used in the treatment of cough and bronchitis and therefore it was our objective to study the effect various extracts of the plant on clonidine and haloperidol induced catalepsy to study its antihistaminic effect. Petroleum ether extract (200 mg/kg, i.p.) of the p...
Guardado en:
| Autores principales: | , , , , , |
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| Formato: | Articulo Comunicacion |
| Lenguaje: | Inglés |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8216 http://www.latamjpharm.org/resumenes/30/4/LAJOP_30_4_2_3.pdf |
| Aporte de: |
| Sumario: | Achyranthes aspera is traditionally used in the treatment of cough and bronchitis and therefore it was our objective to study the effect various extracts of the plant on clonidine and haloperidol induced catalepsy to study its antihistaminic effect. Petroleum ether extract (200 mg/kg, i.p.) of the plant significantly inhibited clonidine-induced catalepsy but not inhibited haloperidol-induced catalepsy. This
proves the antihistaminic activity of the plant. The extract was standardized by HPTLC in presence of
standard β-sitosterol, which proves that the antihistaminic activity may be due to β-sitosterol. |
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