A multivariate strategy for tablet manufacturing optimization

The objective of this work was to develop a multivariate strategy to optimize tablet manufacturing employing mephenesin as model drug. The process variables for granulation step were binders and lubricants types, while the mixture variables included the proportions of binders and lubricants. To red...

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Detalles Bibliográficos
Autores principales: Fernández, Eutimio G., Fernández C., Mirna, Hoang, Hoang Min, Pérez Sánchez, Irela, Guerra, Dayneris, Izquierdo, Adalberto C., Valdes, Rodolfo, Ramos, Mena Cayetana
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
crossed experimental design; mephenesin; multivariate strategy; principal component analysis; tablet manufacturing
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8070
http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_1_10.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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