Determination of dextromethorphan in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

A highly sensitive liquid chromatographic tandem mass spectrometric (LC-MS/MS) method for determination of dextromethorphan in rabbit plasma using triazolam as the internal standard (IS) was developed. Plasma samples were extracted with ethyl acetate and separated on a SB-C18 column with a mobile ph...

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Detalles Bibliográficos
Autores principales: Hu, Lufeng, Wang, Xianqin, Jiang, Haiyan, Xu, Xuegu, Xu, Ren-ai, Lin, Guanyang
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
dextromethorphan; LC-MS/MS; determination; rabbit; pharmacokinetic
Medicamentos
Farmacología
Farmacocinética
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7994
http://www.latamjpharm.org/resumenes/29/5/LAJOP_29_5_2_12.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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