Diphenylpropanoids from quisqualis indica linn. and their anti-staphylococcal activity

Four diphenylpropanoids- 1-(4-hydroxy-3-methoxyphenyl)-2-(4-allyl-2,6-dimethoxyphenoxy)propan-1-ol (1), 1-(3,4-dimethoxyphenyl)-2-(4-allyl-2,6-dimethoxyphenoxy)propan-1-ol (2), 1-(3,4- dime thoxyphenyl ) -2- (4-al lyl -2,6-dime thoxyphenoxy)propan-1-ylac e tat e (3) and 1- (4-hydroxy-3,5- dimethoxyp...

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Detalles Bibliográficos
Autores principales: Jahan, Fatima N., Rahman, Mohammad S., Rahman, M. Mukhlesur, Gibbons, Simon, Masud, Mohammad M., Sadhu, Samir K., Hossain, Mahboob, Hasan, Choudhury M., Rashid, Mohammad A.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2009
Materias:
Farmacia
Fitoquímica
combretaceae; diphenylpropanoids; MRSA; quisqualis indica
Extractos de plantas
Plantas medicinales
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7758
http://www.latamjpharm.org/trabajos/28/2/LAJOP_28_2_2_2_14D3K4PI8H.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
Descripción
Sumario:Four diphenylpropanoids- 1-(4-hydroxy-3-methoxyphenyl)-2-(4-allyl-2,6-dimethoxyphenoxy)propan-1-ol (1), 1-(3,4-dimethoxyphenyl)-2-(4-allyl-2,6-dimethoxyphenoxy)propan-1-ol (2), 1-(3,4- dime thoxyphenyl ) -2- (4-al lyl -2,6-dime thoxyphenoxy)propan-1-ylac e tat e (3) and 1- (4-hydroxy-3,5- dimethoxyphenyl)-2-(4-allyl-2,6-dimethoxyphenoxy) propan-1-ol (4) were isolated from the chloroform soluble fraction of a methanol extract of Quisqualis indica. The structures of these compounds were established unambiguously by MS and a series of 1D and 2D-NMR analyses. All compounds were tested for their anti-staphylococcal activity against a total of five multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus strains and the minimum inhibitory concentrations (MICs) were in the range of 128-256 μg/ml

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