Determination of phenytoin in human plasma by a validated liquid chromatography method and its application to a bioequivalence study

A sensitive and specific method based on liquid chromatography was developed and validated for the determination of phenytoin in human plasma using phenobarbital as internal standard. The drugs were extracted from plasma by liquid-liquid extraction and separated isocratically on a Phenomenex Synerg...

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Autores principales: Dalmora, Sérgio Luiz, Nogueira, Daniele R., Londero, Lidiane F., Santana, Davi P., Gonçalves, Talita M.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2009
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7753
http://www.latamjpharm.org/trabajos/28/2/LAJOP_28_2_1_12_E16P321054.pdf
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