2-D QSAR analysis of benzofuran biphenyl/naphthalenes as potent protein tyrosine phosphatase-1B inhibitors
Insulin resistance is associated with a defect in protein tyrosine phosphorylation in the insulin signal transduction cascade. PTPase enzyme dephosphorylates the active form of insulin receptor and thus attenuates its tyrosine kinase activity, therefore the need of a potent PTPase inhibitor is the r...
Guardado en:
| Autor principal: | Kaushik, Darpan |
|---|---|
| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/7735 http://www.latamjpharm.org/trabajos/28/1/LAJOP_28_1_2_5_9FB0059C44.pdf |
| Aporte de: |
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