Caracterização farmacobotânica de Peumus boldus (Monimiaceae) e avaliação de atividades biológicas do alcalóide boldina

Peumus boldus Molina (Monimiaceae) is a medicinal plant known in Brazil as "boldo" or "boldo-do-chile", and its leaves are popularly used in digestive and hepatic diseases. A pharmacobotanical study was carried out, macro and microscopically features were illustrated and descri...

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Autores principales: Schwanz, Melissa, Nunes, Eliana, Konrath, Eduardo L., Vendruscolo, Giovana S., Silva, Márcia Vignoli da, Henriques, Amélia T., Mentz, Lilian Auler
Formato: Articulo
Lenguaje:Portugués
Publicado: 2008
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7704
http://www.latamjpharm.org/trabajos/27/6/LAJOP_27_6_1_11_OGM187JM50.pdf
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Sumario:Peumus boldus Molina (Monimiaceae) is a medicinal plant known in Brazil as "boldo" or "boldo-do-chile", and its leaves are popularly used in digestive and hepatic diseases. A pharmacobotanical study was carried out, macro and microscopically features were illustrated and described, in an attempt to complement the fourth edition of the Brazilian Pharmacopoea monograph. Some special characters can be used to identify this drug: revolute margined leaves, typical color and texture, covering stellate trichomes, secretory cells, hypoestomatic mesophyll, anomocytic stomata, and crystals. Boldine, the major alkaloid found in this species, exhibited potent antioxidant activity and an unprecedented anticholinesterasic effect, both demonstrated through autobiographic assays.