Síntese e ensaio in vivo de ésteres da indometacina: desenvolvimento de aula prática em Química Medicinal para alunos de pós-graduação

This article shows a Medicinal Chemistry practical class, created and developed by students of the Pharmaceutical Sciences Post-Graduate Program (PPGCF/UFRGS). It describes the planning, synthesis and in vivo biological evaluation of four ester derivatives of the non-steroidal anti-inflammatory dr...

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Detalles Bibliográficos
Autores principales: Cruz, Leticia, Graebin, Cedric S., Viana, Alice, Piato, Ângelo L. S., Ghisleni, Daniela, Santos, Éverton dos, Limberger, Jones, Vaucher, Lauren C., Gnoatto, Simone B., Oliveira, Simone Q. de, Oppe, Tércio P., Schapoval, Elfrides E. S., Eifler-Lima, Vera L.
Formato: Articulo
Lenguaje:Portugués
Publicado: 2008
Materias:
Farmacia
atividade anti-inflamatória; indometacina; Química Medicinal
Ciencias Químicas
Medicina
Alumnos
Agentes Antiinflamatorios
Efectos fisiológicos de las drogas
Evaluación de drogas
anti-inflammatory activity; indomethacin; Medicinal Chemistry
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7686
http://www.latamjpharm.org/trabajos/27/5/LAJOP_27_5_1_11_7BB9NB5L59.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
Descripción
Sumario:This article shows a Medicinal Chemistry practical class, created and developed by students of the Pharmaceutical Sciences Post-Graduate Program (PPGCF/UFRGS). It describes the planning, synthesis and in vivo biological evaluation of four ester derivatives of the non-steroidal anti-inflammatory drug Indomethacin (IndOH) as a proposal for practical classes of Medicinal Chemistry.

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