Opposing effects of bisphosphonates and advanced glycation end-products on osteoblastic cells

Patients with long-standing Diabetes mellitus can develop osteopenia and osteoporosis. We have previously shown that advanced glycation endproducts reduce the bone-forming activity of osteoblasts. Bisphosphonates are used for the treatment of various bone disorders, since they reduce osteoclastic fu...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gangoiti, María Virginia, Cortizo, Ana María, Arnol, Verónica, Felice, Juan Ignacio, McCarthy, Antonio Desmond
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2008
Materias:	Ciencias Exactas bisphosphonates, advanced glycation endproducts, osteoblasts, proliferation, reactive oxygen species Diabetes Mellitus Osteoporosis
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/76584
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

Ejemplares similares

Advanced glycation endproduct-specific receptors in rat and mouse osteoblast-like cells: regulation with stages of differentiation
por: McCarthy, Antonio Desmond, et al.
Publicado: (1999)

Effect of advanced glycation endproducts on the secretion of insulin-like growth factor-I and its binding proteins: role in osteoblast development
por: McCarthy, Antonio Desmond, et al.
Publicado: (2001)

Advanced glycation endproducts interfere with integrin-mediated osteoblastic attachment to a type-I collagen matrix
por: McCarthy, Antonio Desmond, et al.
Publicado: (2004)

AGE-R3/galectin-3 expression in osteoblast-like cells: Regulation by AGEs
por: Mercer, Natalia, et al.
Publicado: (2004)

Advanced Glycation Endproducts and Alendronate Differentially Inhibit Early and Late Osteoclastogenesis <i>in vitro</i>
por: Gangoiti, María Virginia, et al.
Publicado: (2013)

Advanced glycation end-products (AGEs) induce concerted changes in the osteoblastic expression of their receptor RAGE and in the activation of extracellular signal-regulated kinases (ERK)
por: Cortizo, Ana María, et al.
Publicado: (2003)

Regulation of advanced glycation end product (AGE) receptors and apoptosis by AGEs in osteoblast-like cells
por: Mercer, Natalia, et al.
Publicado: (2007)

Osteogenic actions of the anti-diabetic drug metformin on osteoblasts in culture
por: Cortizo, Ana María, et al.
Publicado: (2006)

Advanced glycation end products and strontium ranelate promote osteogenic differentiation of vascular smooth muscle cells in vitro: preventive role of vitamin D
por: Molinuevo, María Silvina, et al.
Publicado: (2017)

Capillary Zone Electrophoresis study of the in vitro albumin glycation process
por: Castañón, M.M., et al.

Capillary Zone Electrophoresis study of the in vitro albumin glycation process
por: Castañon, María Mercedes, et al.
Publicado: (2006)

AGEs and Bone Ageing in Diabetes Mellitus
por: McCarthy, Antonio Desmond, et al.
Publicado: (2013)

Bone-specific alkaline phosphatase activity is inhibited by bisphosphonates: role of divalent cations
por: Vaisman, Diego Natalio, et al.
Publicado: (2005)

Efectos <i>in vivo</i> del ranelato de estroncio sobre células progenitoras de médula ósea de ratas diabéticas
por: Lino, Agustina Berenice, et al.
Publicado: (2016)

Synthesis of a new vanadyl(IV) complex with trehalose (TreVO): insulin-mimetic activities in osteoblast-like cells in culture
por: Barrio, Daniel Alejandro, et al.
Publicado: (2003)

Methods: A new protocol for in vitro red blood cell glycation
por: Batista da Silva, Marcus V., et al.
Publicado: (2021)

Role of oxidative stress in the antitumoral action of a new vanadyl(IV) complex with the flavonoid chrysin in two osteoblast cell lines: relationship with the radical scavenger activity
por: Naso, Luciana Gissella, et al.
Publicado: (2010)

Molecular Characterization of the Glycated Plasma Membrane Calcium Pump
por: González Flecha, F. L., et al.
Publicado: (1999)

Evaluación de la respuesta densitométrica en pacientes con osteoporosis posmenopáusica tratadas con ranelato de estroncio o denosumab
por: Sánchez, Ariel, et al.
Publicado: (2017)

Metformin revisited: Does this regulator of AMP-activated protein kinase secondarily affect bone metabolism and prevent diabetic osteopathy?
por: McCarthy, Antonio Desmond, et al.
Publicado: (2016)

Non-enzymatic glycosylation of a type 1 collagen matrix: effects on osteoblastic development and oxidative stress
por: McCarthy, Antonio Desmond, et al.
Publicado: (2001)

Multi-target heteroleptic palladium bisphosphonate complexes
por: Cipriani, Micaella, et al.
Publicado: (2020)

Experimental in vitro infection of rat osteoblasts with measles virus stimulates osteogenic differentiation
por: Ayala-Peña, V., et al.

Experimental in vitro infection of rat osteoblasts with measles virus stimulates osteogenic differentiation
por: Scolaro, Luis Alberto
Publicado: (2014)

Antitumoral properties of two new vanadyl(IV) complexes in osteoblasts in culture: role of apoptosis and oxidative stress
por: Molinuevo, María Silvina, et al.
Publicado: (2004)

Dairy product consumption and type 2 diabetes in an Argentinian population: is there an association?
por: Baraquet, María Lucía, et al.
Publicado: (2024)

Saxagliptin affects long-bone microarchitecture and decreases the osteogenic potential of bone marrow stromal cells
por: Sbaraglini, María Laura, et al.
Publicado: (2014)

Successful Management of a Severe Case of Bisphosphonates Related Osteonecrosis of the Jaw in a Multiple Myeloma Patient
por: Luchetti, César Gabriel, et al.
Publicado: (2009)

Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents
por: Recher, M., et al.

Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents
por: Szajnman, Sergio Hernán, et al.
Publicado: (2013)

Vanadate-induced nitric oxide production: role in osteoblast growth and differentiation
por: Cortizo, Ana María, et al.
Publicado: (2000)

Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin) : Bioactivity on osteoblast-like cells in culture
por: Etcheverry, Susana B., et al.
Publicado: (2002)

Vanadium derivatives act as growth factor-mimetic compounds upon differentiation and proliferation of osteoblast-like UMR106 cells
por: Cortizo, Ana María, et al.
Publicado: (1995)

Effects of fructose-induced metabolic syndrome on rat skeletal cells and tissue, and their responses to metformin treatment
por: Felice, Juan Ignacio, et al.
Publicado: (2017)

Insulin-mimetic action of vanadium compounds on osteoblast-like cells in culture
por: Etcheverry, Susana B., et al.
Publicado: (1997)

Tetraethyl vinylidenebisphosphonate: A versatile synthon for the preparation of bisphosphonates
por: Rodriguez, J.B.

Tetraethyl vinylidenebisphosphonate: A versatile synthon for the preparation of bisphosphonates
por: Rodríguez, Juan Bautista
Publicado: (2014)

Preclinical toxicology of bisphosphonates
por: Mondelo, N., et al.

Preclinical toxicology of bisphosphonates
Publicado: (1997)

Myelodysplastic syndrome, osteoporosis and medication-related osteonecrosis of the jaw: a case report
por: Leonardi, Nicolás, et al.
Publicado: (2020)