Liver Nuclear Lipid Droplets are a dynamic nuclear domain

The cell nucleus (N) is a highly compartmentalized organelle characterized by several dynamic domains. In the laboratory it was shown for the first time that nuclear lipid droplets (nLD) are a new class of subnuclear bodies and a nuclear domain where neutral lipids are stored and organized. These dr...

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Detalles Bibliográficos
Autores principales: Lagrutta, Lucía Carolina, Layerenza, Juan Pablo, Montero Villegas, Sandra, Sisti, María Susana, García de Bravo, Margarita María, Ves Losada, Ana
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2013
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/60657
http://revista.med.unlp.edu.ar/archivos/201312/62-Lagrutta.pdf
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Sumario:The cell nucleus (N) is a highly compartmentalized organelle characterized by several dynamic domains. In the laboratory it was shown for the first time that nuclear lipid droplets (nLD) are a new class of subnuclear bodies and a nuclear domain where neutral lipids are stored and organized. These droplets would be built up around a hydrophobic core of TAG and CE enriched in oleic acid and surrounded by a monolayer of polar lipids along with C and associated proteins. nLD components represent an exceedingly small proportions of the total cell components.