The importance of the Thr<SUP>17</SUP> residue of phospholamban as a phosphorylation site under physiological and pathological conditions

The sarcoplasmic reticulum (SR) Ca<SUP>2+</SUP>-ATPase (SERCA2a) is under the control of an SR protein named phospholamban (PLN). Dephosphorylated PLN inhibits SERCA2a, whereas phosphorylation of PLN at either the Ser<SUP>16</SUP> site by PKA or the Thr<SUP>17</SUP&g...

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Detalles Bibliográficos
Autores principales:	Mattiazzi, Alicia Ramona, Mundiña-Weilenmann, Cecilia, Vittone, Leticia, Said, María Matilde, Kranias, E. G.
Formato:	Articulo Revision
Lenguaje:	Inglés
Publicado:	2006
Materias:	Ciencias Médicas isoprenaline β-adrenergic stimulation acidosis ischemia serine threonine phospholamban Thr17 site phosphorylation hypercapnia pathophysiology physiology
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/37573 http://www.scielo.br/pdf/bjmbr/v39n5/6159.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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