Junín virus infection of human hematopoietic progenitors impairs in vitro proplatelet formation and platelet release via a bystander effect involving type I IFN signaling

Argentine hemorrhagic fever (AHF) is an endemo-epidemic disease caused by Junín virus (JUNV), a member of the arenaviridae family. Although a recently introduced live attenuated vaccine has proven to be effective, AHF remains a potentially lethal infection. Like in other viral hemorrhagic fevers (VH...

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Detalles Bibliográficos
Autores principales: Pozner, Roberto G., Ure, Agustín Enrique, Jaquenod De Giusti, Carolina, D'Atri, Lina P., Italiano, Joseph E., Torres, Oscar, Romanowski, Víctor, Schattner, Mirta, Gómez, Ricardo Martín
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Bioquímica
Fiebre Hemorrágica Americana
Arenaviridae
Trombocitopenia
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/29442
http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1000847
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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