The interaction between sulfathiazole and cobalt(II): potentiometric studies

Potentiometric studies of sulfathiazole (HST) in the presence and absence of cobalt(II) were performed. Equilibrium constants for the formation of the detected species, [Co(ST)]<sup>+</sup> and [Co(ST)(OH)], are reported. UV-Vis spectrophotometric measurements suggest that the coordinati...

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Autores principales: Bellú, Sebastián, Rizzotto, Marcela, Okulik, Nora Beatriz, Jubert, Alicia Haydeé
Formato: Articulo
Lenguaje:Inglés
Publicado: 2007
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/29433
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000500016&lng=en&nrm=iso&tlng=en
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Sumario:Potentiometric studies of sulfathiazole (HST) in the presence and absence of cobalt(II) were performed. Equilibrium constants for the formation of the detected species, [Co(ST)]<sup>+</sup> and [Co(ST)(OH)], are reported. UV-Vis spectrophotometric measurements suggest that the coordination Co(II)-sulfathiazole might be through a N atom, which, in agreement with MO calculations, could be a thiazolic one. In spite of sulfonamides being better ligands at pH >7, [Co(ST)]<sup>+</sup> was found at pH ≈ 3.