Regulation of subcellular location and activity of Cdc2-cyclinb1 is involved in bendamustine-induced G2 arrest
Bendamustine is a multifunctional alkylating agent for the treatment of multiple myeloma, with the G2/M arrest-induction ability in human multiple myeloma RPMI-8226 cells, but the mechanism remains ambiguous. In this study, we found bendamustine caused the G2 arrest in 24 h, regulated the phosphoryl...
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| Autores principales: | Lin, Guan-Yu, He, Ling-Juan, Yan, Yan, Wang, Duo-Duo, Zhuang, Kai-Zan, Zhu, Hong, Yang, Bo |
|---|---|
| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/25754 http://www.latamjpharm.org/resumenes/31/7/LAJOP_31_7_1_18.pdf |
| Aporte de: |
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