The effects of (+)-Gossypol on 11β-HSD and the concentration of corticosterone and dehydrocorticosterone in mice serum and tissues

11β-hydroxysteroid dehydrogenase (11β-HSD) plays an important part in mediating glucocorticoid action, catalyzing the interconversion of corticosterone (B) and dehydrocorticosterone (A) in rodents. The aim of our study is to investigate the effects of (+)-gossypol (G+) on 11β-HSD. Adult ICR mice wer...

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Detalles Bibliográficos
Autores principales: Qiu, Xiangjun, Li, Wanshu, Li, Junwei, Wang, Mengmeng, Wang, Jia, Chen, Lianguo, Sun, Wei, Zhang, Likang, Wen, Congcong, Ge, Renshan, Hu, Guoxin
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Corticosterona
Suero
Tejidos
11-beta-Hidroxiesteroide Deshidrogenasas
Corticosterone
Dehydrocorticosterone
(+)-Gossypol
HPLC
11β-hydroxysteroid Dehydrogenase
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/20206
http://www.latamjpharm.org/resumenes/31/4/LAJOP_31_4_2_1.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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