Effect of a non-methoxylated N-trimethyl chitosan chloride derivative over capreomycin sulfate permeability in CaCo-2 cell monolayers

The effect of N-trimethylchitosan chloride on the intestinal permeability of capreomycin sulfate, a polypeptide antibiotic, using an in vitro model, was evaluated. To improve the mucoadhesivity and permeation enhancer properties of N-trimethylchitosan chloride, it was used a synthetic pathway that s...

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Autores principales: Plessing, Carlos von, Torres, Pablo, Rivas, Coralia, Guzmán, Paula, Núñes, Christian, Sepúlveda, Jacqueline
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/18098
http://www.latamjpharm.org/resumenes/31/2/LAJOP_31_2_1_11.pdf
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