Activation of smooth muscle BK channels by hydrochlorothiazide requires cell integrity and the presence of BK β1-subunits

Thiazide-like diuretics are one of the most commonly used drugs to treat arterial hypertension, with their efficacy being linked to their chronic vasodilatory effects. Previous studies have suggested that activation of the large conductance voltage- and Ca2+-dependent K+ (BK) channel (Slo 1, MaxiK c...

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Detalles Bibliográficos
Autores principales:	Martín, Pedro, Moncada, Melisa, Kuntamallappanavar, Guruprasad, Dopico, Alex M., Milesi, María Verónica
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2017
Materias:	Ciencias Exactas BK channel Slo1 human umbilical artery thiazide hydrochlorothiazide beta-1 subunit vascular smooth muscle cells
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/167271
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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