Spontaneous adsorption of silver nanoparticles on Ti/TiO₂ surfaces : Antibacterial effect on "Pseudomonas aeruginosa"

Titanium is a corrosion-resistant and biocompatible material widely used in medical and dental implants. Titanium surfaces, however, are prone to bacterial colonization that could lead to infection, inflammation, and finally to implant failure. Silver nanoparticles (AgNPs) have demonstrated an excel...

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Autores principales: Flores, Constanza Y., Díaz, Carolina, Rubert, Aldo Alberto, Benitez, Guillermo Alfredo, Moreno, Mario Sergio Jesús, Fernández Lorenzo de Mele, Mónica Alicia, Salvarezza, Roberto Carlos, Schilardi, Patricia Laura, Vericat, Carolina
Formato: Articulo
Lenguaje:Español
Publicado: 2010
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/162924
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Sumario:Titanium is a corrosion-resistant and biocompatible material widely used in medical and dental implants. Titanium surfaces, however, are prone to bacterial colonization that could lead to infection, inflammation, and finally to implant failure. Silver nanoparticles (AgNPs) have demonstrated an excellent performance as biocides, and thus their integration to titanium surfaces is an attractive strategy to decrease the risk of implant failure. In this work a simple and efficient method is described to modify Ti/TiO₂ surfaces with citrate-capped AgNPs. These nanoparticles spontaneously adsorb on Ti/TiO₂, forming nanometer-sized aggregates consisting of individual AgNPs that homogeneously cover the surface. The modified AgNP– Ti/TiO₂ surface exhibits a good resistance to colonization by "Pseudomonas aeruginosa", a model system for biofilm formation.