Ultrastructural changes of Henle's loop epithelial cells in the kidney of mice treated with low doses of Ochratoxin A
Renal changes in mice daily treated with low doses of ochratoxin A (OA; 50-400μg/kg) for up to 4 weeks were investigated by electron microscope. Except the mice treated with 50μg/kg of OA for 4 weeks, all treated mice showed the following changes in the epithelial cells of Henle's loop: (1) deg...
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| Autores principales: | , , , , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
1994
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/145292 |
| Aporte de: |
| Sumario: | Renal changes in mice daily treated with low doses of ochratoxin A (OA; 50-400μg/kg) for up to 4 weeks were investigated by electron microscope. Except the mice treated with 50μg/kg of OA for 4 weeks, all treated mice showed the following changes in the epithelial cells of Henle's loop: (1) degeneration of mitochondria, (2) increment of endoplasmic reticula, and (3) increase in the number and size of lysosomes and myelin figures. |
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