Genotoxicity of the herbicide imazethapyr in mammalian cells by oxidative DNA damage evaluation using the Endo III and FPG alkaline comet assays

We evaluated the role of oxidative stress in the genotoxic damage induced by imazethapyr (IMZT) and its formulation Pivot® in mammalian CHO-K1 cell line. Using the alkaline comet assay, we observed that a concentration of 0.1 μg/mL of IMZT or Pivot® was able to induce DNA damage by increasing the fr...

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Detalles Bibliográficos
Autores principales: Soloneski, Sonia María Elsa, Ruiz de Arcaute, Celeste, Nikoloff, Noelia, Larramendy, Marcelo Luis
Formato: Articulo
Lenguaje:Inglés
Publicado: 2017
Materias:
Ciencias Naturales
Comet assay
Imazethapyr-based formulation
Imidazolinone herbicides
Oxidative DNA damage
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/141436
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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