Extranodal follicular lymphoma in the lung of a free-ranging red deer (<i>Cervus elaphus</i>)

A hunted free-ranging female red deer (<i>Cervus elaphus</i>) from a region near the Nahuel Huapi National Park, Northern Patagonia, Argentina, had a focally extensive peribronchial lymphoid proliferative lesion in the lung characterized by formation of multiple follicles, with prominent...

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Autores principales: Chang Reissig, Elizabeth, Valli, Victor E., Pesavento, Patricia A., Massone, Adriana Raquel, Iovanitti, Beatriz, Gimeno, Eduardo Juan, Uzal, Francisco A.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2013
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/138554
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Sumario:A hunted free-ranging female red deer (<i>Cervus elaphus</i>) from a region near the Nahuel Huapi National Park, Northern Patagonia, Argentina, had a focally extensive peribronchial lymphoid proliferative lesion in the lung characterized by formation of multiple follicles, with prominent germinal centers lacking mantle zone cells and antigen-related polarity. On examination of immunohistochemically stained tissues, a predominance of B cells (cluster of differentiation [CD]20 positive) with only a few scattered T cells (CD3 positive) were present. The histologic and immunohistochemical characteristics are consistent with follicular lymphoma, which is frequently seen in human beings and less frequently in domestic animals.