Early ultrastructural changes of thymocytes in T-2 toxicated mice

Subcellular changes of mouse thymocytes after T-2 intoxication were observed for up to 48 hours after injection (HAI). The following changes were observed mainly in cortical lymphocytes at 8 and 16HAI: (1) nuclear projections, (2) nuclear macrocleft, and (3) characteristic features of apoptosis. Con...

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Detalles Bibliográficos
Autores principales: Quiroga, María Alejandra, Itagaki, Shin-ichi, Doi, Kunio
Formato: Articulo
Lenguaje:Inglés
Publicado: 1993
Materias:
Ciencias Veterinarias
Mice
T-2 toxin
Thymus
Ultrastructure
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/138209
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
Descripción
Sumario:Subcellular changes of mouse thymocytes after T-2 intoxication were observed for up to 48 hours after injection (HAI). The following changes were observed mainly in cortical lymphocytes at 8 and 16HAI: (1) nuclear projections, (2) nuclear macrocleft, and (3) characteristic features of apoptosis. Conclusively, it is suggested that apoptosis is partially involved in the early development of thymic lesions by T-2 toxin.

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