<i>Calodium hepaticum</i> (Nematoda: Capillariidae) in wild rodent populations from Argentina

<i>Calodium hepaticum</i> (Nematoda; Capillariidae) is a parasitic nematode of mammals with a cosmopolitan distribution. Adults of this nematode can infect the liver of many mammalian species, including humans, but the main hosts are members of the superfamily Muroidea. Among these, <...

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Autores principales: Fantozzi, María Cecilia, Robles, María del Rosario, Peña, Fiama E., Antoniazzi, Leandro Raúl, Beldomenico, Pablo Martín, Monje, Lucas Daniel
Formato: Articulo
Lenguaje:Inglés
Publicado: 2018
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/134024
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Sumario:<i>Calodium hepaticum</i> (Nematoda; Capillariidae) is a parasitic nematode of mammals with a cosmopolitan distribution. Adults of this nematode can infect the liver of many mammalian species, including humans, but the main hosts are members of the superfamily Muroidea. Among these, <i>Rattus</i> spp. have the highest apparent prevalences reported worldwide. There are only two reports of <i>C. hepaticum</i> infecting Sigmodontinae species (Muroidea: Cricetidae). In this survey, we examined the occurrence of <i>C. hepaticum</i> in two assemblages of Sigmodontinae rodents from Argentina (Santa Fe and Entre Rios provinces). The diagnosis was made by morphological features, histopathological exam, and molecular characterization of 18S ribosomal RNA gene region. Here, we show that <i>C. hepaticum</i> is a common parasite of Sigmodontinae. We report the infection in six species (all new hosts): <i>Akodon azarae</i>, <i>Calomys callidus</i>, <i>Calomys venustus</i>, <i>Oligoryzomys flavescens</i>, <i>Oligoryzomys nigripes</i>, and <i>Oxymycterus rufus</i>. This is the first report of <i>C. hepaticum</i> in Sigmodontinae rodents from Argentina and the second record in this subfamily for South America. It is also the first confirmation of <i>C. hepaticum</i> infection in Sigmodontinae by molecular diagnosis. The genetic findings and the prevalences observed, together with the existing information on <i>C. hepaticum</i>, lead us to propose that <i>Rattus</i> spp. brought <i>C. hepaticum</i> to the New World exposing Sigmodontinae rodents, which are frequently infected by this parasite. The high prevalence of infection in <i>A. azarae</i> (41.2%) suggests that this host may be playing an important role in <i>C. hepaticum</i> dynamics in the New World.