Ensemble learning application to discover new trypanothione synthetase inhibitors
Trypanosomatid-caused diseases are among the neglected infectious diseases with the highest disease burden, affecting about 27 million people worldwide and, in particular, socio-economically vulnerable populations. Trypanothione synthetase (TryS) is considered one of the most attractive drug targets...
Guardado en:
| Autores principales: | Alice, Juan Ignacio, Bellera, Carolina Leticia, Benítez Boné, Diego Raúl, Comini, Marcelo A., Duchowicz, Pablo Román, Talevi, Alan |
|---|---|
| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2021
|
| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/133709 |
| Aporte de: |
Ejemplares similares
-
Búsqueda de nuevos farmacos antichagásicos inhibidores de la tripanotión sintetasa
por: Alice, Juan Ignacio
Publicado: (2020) -
Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
por: Benítez, Diego, et al.
Publicado: (2020) -
Application of linear discriminant analysis in the virtual screening of antichagasic drugs through trypanothione reductase inhibition
por: Prieto, Julián José, et al.
Publicado: (2006) -
SECA: a stepwise algorithm for construction of neural networks ensembles
por: Granitto, Pablo Miguel, et al.
Publicado: (2001) -
Diseño y síntesis de inhibidores del camino biosintético de tripanotiona
por: Ravaschino, Esteban Luis
Publicado: (2006)