Insulin-deficient diabetes-induced bone microarchitecture alterations are associated with a decrease in the osteogenic potential of bone marrow progenitor cells: Preventive effects of metformin

Aims: Diabetes mellitus is associated with metabolic bone disease and increased lowimpact fractures. The insulin-sensitizer metformin possesses in vitro, in vivo and ex vivo osteogenic effects, although this has not been adequately studied in the context of diabetes. We evaluated the effect of insul...

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Autores principales: Tolosa, María José Anahí, Chuguransky, Sara Rocío, Sedlinsky, Claudia, Schurman, León, McCarthy, Antonio Desmond, Molinuevo, María Silvina, Cortizo, Ana María
Formato: Articulo
Lenguaje:Inglés
Publicado: 2013
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/130692
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