RNA-sequencing analysis of a multistep and hit-and-run cell and animal model of KSHV tumorigenesis reveal the roles of mutations, CpG methylation, and viral-infection footprints in oncogenesis

Human viral oncogenesis is the consequence of cell transformation mediated by virally encoded oncogenes in combination with host oncogenic alterations. Kaposi’s sarcoma (KS), caused by the Kaposi’s sarcoma-associated herpes virus (KSHV), is an AIDS-associated cancer characterized by angiogenesis and...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Naipauer, Julian, Salyakina, Daria, Journo, Guy, Rosario, Santas, Williams, Sion L., Abba, Martín Carlos, Shamay, Meir, Mesri, Enrique A.
Formato:	Articulo Preprint
Lenguaje:	Inglés
Publicado:	2019
Materias:	Ciencias Médicas Gene Cpg site Oncovirus Lytic cycle Dna methylation Methylation Epigenetics Cancer research Carcinogenesis Biology
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/125353
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

Ejemplares similares

High-throughput sequencing analysis of a "hit and run" cell and animal model of KSHV tumorigenesis
por: Naipauer, Julian, et al.
Publicado: (2020)

Corrigendum to “CpG-ODN formulated with a nanostructure as adjuvant for anticrotalic serum production. Studies in mice” [Toxicon 215 (2022) 28–36]
por: Fusco, Luciano S., et al.
Publicado: (2025)

A Non-Coding RNA Network Involved in KSHV Tumorigenesis
por: Naipauer, Julián, et al.
Publicado: (2021)

A non-coding RNA network involved in KSHV tumorigenesis
por: Naipauer, Julian, et al.
Publicado: (2021)

Vacunas : nanoestructura de tipo cristal líquido como sistema portador del adyuvante CpG-ODN para la inducción de una respuesta inmune
por: Sánchez Vallecillo, María Fernanda
Publicado: (2020)

Photodegradation of methyl thioglycolate particles as a proxy for organosulphur containing droplets
por: Seng, Samantha, et al.
Publicado: (2018)

Formulación de un antígeno proteico modelo y CpG-ODN con una nanoestructura de cristal líquido: estudio de la respuesta inmune innata y su repercusión en la respuesta inmune adaptativa
por: Marin, Constanza
Publicado: (2023)

Escherichia coli coculture for de novo production of esters derived of methyl-branched alcohols and multi-methyl branched fatty acids
por: Bracalente, Fernando, et al.
Publicado: (2022)

PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment
por: Naipauer, Julian, et al.
Publicado: (2019)

Análisis de nuevos vehículos y adyuvantes para inmunización con antígenos de Staphylococcus aureus utilizando diferentes modelos experimentales
por: Reidel, Ivana Gabriela
Publicado: (2021)

Some Theoretical Considerations About the Excited Singlet and Triplet States of Diformamide and N-Methyl Diformamide
por: Marañon, Julio, et al.
Publicado: (1977)

Nutritive value of methyl linoleate and its thermal decomposition products
por: Bottino, Néstor Rodolfo
Publicado: (1962)

Location of tryptophan residues in free and membrane bound Escherichia coli α-hemolysin and their role on the lytic membrane properties
por: Verza, Georgina, et al.
Publicado: (2000)

GM-CSF enhances a CpG-independent pathway of neutrophil activation triggered by bacterial DNA
por: Bass, J.I.F., et al.

GM-CSF enhances a CpG-independent pathway of neutrophil activation triggered by bacterial DNA
por: Gabelloni, María Laura, et al.
Publicado: (2008)

InVet 2021, 23 (2): 01-10 ARTÍCULO DE INVESTIGACIÓN ISSN...
por: Motter, M.M., et al.
Publicado: (2021)

The Molecular Structure of 4-Methyl Benzenesulfonyl Chloride
por: Rigotti, Guillermo, et al.
Publicado: (1986)

TiO2 nanowires doped with hæmatite nanoparticles for enhanced photocatalytic degradation of methyl orange.
por: Vinuesa, Ariel José, et al.
Publicado: (2022)

The impact of HPMC structure in the modulation of in vitro lipolysis: The role of bile salts
por: Pizones Ruiz-Henestrosa, V.M., et al.

Methylation analysis of carrageenans from the seaweed Iridaea undulosa
por: Matulewicz, M.C., et al.

Methylation analysis of carrageenans from the seaweed Iridaea undulosa
por: Matulewicz, María Cristina, et al.
Publicado: (1980)

The impact of HPMC structure in the modulation of in vitro lipolysis: The role of bile salts
por: Camino, Nerina Andrea, et al.
Publicado: (2017)

Atypical epigenetic mark in an atypical location: Cytosine methylation at asymmetric (CNN) sites within the body of a non-repetitive tomato gene
por: González, R.M., et al.
Publicado: (2011)

Atypical epigenetic mark in an atypical location: Cytosine methylation at asymmetric (CNN) sites within the body of a non-repetitive tomato gene
por: González, R.M., et al.

Atypical epigenetic mark in an atypical location: Cytosine methylation at asymmetric (CNN) sites within the body of a non-repetitive tomato gene
por: Gonzalez, Rodrigo Matias, et al.
Publicado: (2011)

Atypical epigenetic mark in an atypical location: Cytosine methylation at asymmetric (CNN) sites within the body of a non-repetitive tomato gene
por: González, R.M., et al.
Publicado: (2011)

Alternaria toxins in Argentinean wheat, bran, and flour
por: Romero Bernal, Á.R., et al.

Alternaria toxins in Argentinean wheat, bran, and flour
Publicado: (2019)

Effects on chlorophyll and carotenoid contents in different grape varieties (Vitis vinifera L.) after nitrogen and elicitor foliar applications to the vineyard
por: Gutiérrez- Gamboa, Gastón, et al.
Publicado: (2020)

Effects on chlorophyll and carotenoid contents in different grape varieties (Vitis vinifera L.) after nitrogen and elicitor foliar applications to the vineyard
por: Gutiérrez- Gamboa, Gastón, et al.
Publicado: (2020)

Aquatic ecotoxicology: Native freshwater gastropods from Argentina
por: Cossi, P.F., et al.

Aquatic ecotoxicology: Native freshwater gastropods from Argentina
Publicado: (2017)

Effect of lead acetate on the in vitro engulfment and killing capability of toad (<i>Bufo arenarum</i>) neutrophils
por: Rosenberg, Carolina Elena, et al.
Publicado: (2003)

Cold water-soluble polysaccharides from tetrasporic Pterocladia capillacea
por: Errea, M.I., et al.

Cold water-soluble polysaccharides from tetrasporic Pterocladia capillacea
por: Errea, María Inés, et al.
Publicado: (1994)

Phospholipid methyltransferase activity in diabetic rat fat cells : Effect of isoproterenol and insulin
por: Chiappe de Cingolani, Gladys Ethel
Publicado: (1992)

Aging and rejuvenation - a modular epigenome model
por: Chiavellini, Priscila, et al.
Publicado: (2021)

Synthesis and antifungal activity of bile acid-derived oxazoles
por: Fernández, L.R., et al.

Synthesis and antifungal activity of bile acid-derived oxazoles
por: Palermo, Jorge Alejandro
Publicado: (2016)

Straightforward synthesis of derivatives of D- and L-galactonic acids as precursors of stereoregular polymers
por: Romero Zaliz, C.L., et al.