Stereoselective Synthesis of Highly Substituted Tetrahydropyrans through an Evans Aldol-Prins Strategy

A direct and general method for the synthesis of naturally occurring 2,3,4,5,6-pentasubstituted tetrahydropyrans has been developed, employing β,γ-unsaturated N-acyl oxazolidin-2-ones as key starting materials. The combination of the Evans aldol addition and the Prins cyclization allowed the diaster...

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Detalles Bibliográficos
Autores principales: Álvarez Méndez, Sergio J., Fariña Ramos, Marta, Villalba, María Luisa, Perretti, Marcelle D., García, Celina, Moujir, Laila, Ramírez, Miguel A., Martín, Víctor S.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2018
Materias:
Ciencias Exactas
tetrahydropyrans
alcohols
Evans Aldol-Prins Strategy
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/124083
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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