Pre-Existing Tumoral B Cell Infiltration and Impaired Genome Maintenance Correlate with Response to Chemoradiotherapy in Locally Advanced Rectal Cancer

Locally advanced rectal cancer (LARC) remains a medical challenge. Reliable biomarkers to predict which patients will significantly respond to neoadjuvant chemoradiotherapy (nCRT) have not been identified. We evaluated baseline genomic and transcriptomic features to detect differences that may help...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sendoya, Juan M., Iseas, Soledad, Coraglio, Mariana, Golubicki, Mariano, Robbio, Juan, Salanova, Ruben, Kujaruk, Mirta, Mikolaitis, Vanesa, Rizzolo, Mariana, Ruiz, Gonzalo, Cabanne, Ana, Gualdrini, Ubaldo, Mendez, Guillermo, Hirmas, Stella, Rotondaro, Cecilia, Viglino, Julieta, Eleta, Martín, Fernandez, Elmer, Abba, Martín Carlos, Podhajcer, Osvaldo, Roca, Enrique, Llera, Andrea S.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2020
Materias:
Medicina
rectal cancer
immune response
gene expression
neoadjuvant chemoradiotherapy
biomarker
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/107940
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7464257&blobtype=pdf
https://www.mdpi.com/2072-6694/12/8/2227
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

Ejemplares similares

Ejemplares similares