Analysis of ventilator induced lung injury impact in lung and cardiac tissue in a murine model

Mechanical ventilation (MV) with high tidal volumes (Vt) leads to enormous biophysical lung damage, both in patients and in experimental animal models. From a biological point of view, however, the inflammatory response triggered by high Vt-MV and its association with the development of multisystem...

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Autores principales: Correger, Enrique, Marcos, Josefina, Sotelo, D. E., Beldarrain, M., Stringa, Pablo Luis, Laguens, Graciela, Lofeudo, Juan Manuel, Vittone, Leticia
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2015
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/107836
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4797001&blobtype=pdf
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Sumario:Mechanical ventilation (MV) with high tidal volumes (Vt) leads to enormous biophysical lung damage, both in patients and in experimental animal models. From a biological point of view, however, the inflammatory response triggered by high Vt-MV and its association with the development of multisystem organ failure is still under study.