Amino acid substitution in <i>Cryptococcus neoformans</i> lanosterol 14-α-demethylase involved in fluconazole resistance in clinical isolates

The molecular basis of fluconazole resistance in <i>Cryptococcus neoformans</i> has been poorly studied. A common azole resistance mechanism in <i>Candida</i> species is the acquisition of point mutations in the <i>ERG11</i> gene encoding the enzyme lanosterol 14-...

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Detalles Bibliográficos
Autores principales: Bosco Borgeat, María E., Mazza, Mariana, Taverna, Constanza G., Córdoba, Susana Beatriz, Murisengo, Omar A., Vivot, Walter, Davel, Graciela
Formato: Articulo
Lenguaje:Inglés
Publicado: 2016
Materias:
Ciencias Veterinarias
Ciencias Médicas
Cryptococcus neoformans
Fluconazole resistance
ERG11 gene
amino acid substitution
mutation
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/106345
https://www.sciencedirect.com/science/article/pii/S0325754116300013
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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