Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways

Aims Linalool is a plant-derived monoterpene with anticancer activity, however its mechanisms of action remain poorly understood. The aim of this work was to elucidate the anticancer mechanisms of action of linalool in hepatocellular carcinoma (HCC) HepG2 cells. Main methods Cell viability and proli...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Rodenak Kladniew, Boris Emilio, Castro, María Agustina, Stärkel, Peter, De Saeger, Christine, García de Bravo, Margarita María, Crespo, Rosana
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2018
Materias:
Bioquímica
Biología
Akt/mTOR
Apoptosis
Cell cycle arrest
Hepatocellular carcinoma cells
Linalool
Ras/MAPKs
Reactive oxygen species
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/104731
http://hdl.handle.net/11336/96536
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

Ejemplares similares

Ejemplares similares